Activation of innate immune sensors by viruses and self: DNA’s identity crisis?
Bâtiment Jean Bernard Hôpital Saint-Louis, 16 rue de la Grange aux Belles, ParisNicolas MANEL - Laboratory Innate Immunity, U932, Institut Curie, Paris, France The ability to distinguish self vs non-self [...]
Epigenome maintenance in response to DNA damage
Bâtiment Jean Bernard Hôpital Saint-Louis, 16 rue de la Grange aux Belles, ParisSophie POLO - Laboratory of Epigenome Integrity, Epigenetics & Cell Fate Centre, CNRS/Université de Paris, France The response [...]
Immunosurveillance escape of senescent and cancer cells: a cause of age-associated diseases?
Bâtiment Jean Bernard Hôpital Saint-Louis, 16 rue de la Grange aux Belles, ParisJulien CHERFILS-VICINI - Institut for the Recherche of Cancer and Aging, Nice, France As we age, senescent cells [...]
The dichotomy of DNA methylation in spermatogenesis: Protect or program
Bâtiment Jean Bernard Hôpital Saint-Louis, 16 rue de la Grange aux Belles, ParisDeborah BOURC’HIS - UMR 3215 - INSERM U934, « Epigenetic Decisions and Reproduction», Institut Curie, Paris, France DNA [...]
Exploring and exploiting secretory transport in mammalian cells
Bâtiment Jean Bernard Hôpital Saint-Louis, 16 rue de la Grange aux Belles, ParisFranck PEREZ - UMR 144, « Dynamics of Intra-cellular organization », Institut Curie, Paris, France To regulate their homeostasis [...]
Chronic replication stress as a source of genomic instability and inflammation
Bâtiment Jean Bernard Hôpital Saint-Louis, 16 rue de la Grange aux Belles, ParisPhilippe PASERO - Institute of Human Genetics, CNRS & University of Montpellier, Montpellier, France Replication stress (RS) is [...]
Dynamics of chromatin states in breast cancer
Bâtiment Jean Bernard Hôpital Saint-Louis, 16 rue de la Grange aux Belles, ParisCéline VALLOT – Laboratoire “Dynamics of epigenetic plasticity in cancer”, Institut Curie, Paris The dynamic nature of chromatin [...]